4:2 Being grieved. There were three classes of assailants: priests, military, and Sadducees. They had three grounds for action: (1) that Peter and John taught the people, (2) that they taught in the name of Christ (Ac 4:18), and (3) that they bore witness of the resurrection.
And preached through Jesus the resurrection from the dead. The last doctrine, of the resurrection, uprooted the creed of the Sadducees (see notes on Mat 22:23 Ac 23:8). While Jesus lived, his assailants were chiefly Pharisees; when his apostles began to preach his resurrection the Sadducees came to the front as his chief opposers. This will be noted throughout Acts.
4:2 The priests being grieved - That the name of Jesus was preached to the people; especially they were offended at the doctrine of his resurrection; for as they had put him to death, his rising again proved him to be the Just One, and so brought his blood upon their heads. The priests were grieved, lest their office and temple services should decline, and Christianity take root, through the preaching of the apostles, and their power of working miracles: the captain of the temple - Being concerned to prevent all sedition and disorder, the Sadducees - Being displeased at the overturning of all their doctrines, particularly with regard to the resurrection.
4:1-4 The apostles preached through Jesus the resurrection from the dead. It includes all the happiness of the future state; this they preached through Jesus Christ, to be had through him only. Miserable is their case, to whom the glory of Christ's kingdom is a grief; for since the glory of that kingdom is everlasting, their grief will be everlasting also. The harmless and useful servants of Christ, like the apostles, have often been troubled for their work of faith and labour of love, when wicked men have escaped. And to this day instances are not wanting, in which reading the Scriptures, social prayer, and religious conversation meet with frowns and checks. But if we obey the precepts of Christ, he will support us.