16:12 And from thence to Philippi. Only a few miles distant. They sought it at once, because it was the chief city of that part of Macedonia. The apostles tried to leaven the centers of influence with the Gospel. The city had been rebuilt about 400 years before this by Philip, the father of Alexander the Great, who named it after himself. It was famous as the place of the decisive battle between Brutus and Cassius on the one hand, and Mark Antony and Octavius, afterwards Augustus Caesar, upon the other.
A colony. A Roman colony was a settlement of Romans in a foreign country, with all the privileges of Romans. The colony had its own senate, its own magistrates, observed all the Roman forms, and was a miniature Rome. This colony had been established by Caesar Augustus, who settled at this place a multitude of the partisans of his rival, Mark Antony, after the death of the latter. Philippi is now a small village named Filiba.
16:12 The first city - Neapolis was the first city they came to in that part of Macedonia which was nearest to Asia: in that part which was farthest from it, Philippi. The river Strymon ran between them. Philippi was a Roman colony.
16:6-15 The removals of ministers, and the dispensing the means of grace by them, are in particular under Divine conduct and direction. We must follow Providence: and whatever we seek to do, if that suffer us not, we ought to submit and believe to be for the best. People greatly need help for their souls, it is their duty to look out for it, and to invite those among them who can help them. And God's calls must be complied with readily. A solemn assembly the worshippers of God must have, if possible, upon the sabbath day. If we have not synagogues, we must be thankful for more private places, and resort to them; not forsaking the assembling together, as our opportunities are. Among the hearers of Paul was a woman, named Lydia. She had an honest calling, which the historian notices to her praise. Yet though she had a calling to mind, she found time to improve advantages for her soul. It will not excuse us from religious duties, to say, We have a trade to mind; for have not we also a God to serve, and souls to look after? Religion does not call us from our business in the world, but directs us in it. Pride, prejudice, and sin shut out the truths of God, till his grace makes way for them into the understanding and affections; and the Lord alone can open the heart to receive and believe his word. We must believe in Jesus Christ; there is no coming to God as a Father, but by the Son as Mediator.