4:21 Salute every saint. Where he knew so many he could not single out individuals for special greetings, but salutes all.

The brethren who are with me. Such brethren as Timothy and other fellow-laborers, who were now in Rome.

4:20-23 The apostle ends with praises to God. We should look upon God, under all our weakness and fears, not as an enemy, but as a Father, disposed to pity us and help us. We must give glory to God as a Father. God's grace and favour, which reconciled souls enjoy, with the whole of the graces in us, which flow from it, are all purchased for us by Christ's merit, and applied by his pleading for us; and therefore are justly called the grace of our Lord Jesus Christ.